PCDHGC3

Across TCGA patient cohorts, PCDHGC3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,541 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PCDHGC3-associated genes across cancer lineages are PLAUR, C12orf45, and S100A9. Each is linked with PCDHGC3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PCDHGC3-to-partner and partner-to-PCDHGC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHGC3 versus PLAUR in PDAC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGC3→partner) and Y-score (partner→PCDHGC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PLAUR →	+0.707	+0.528	.006	.008	3	3
HNSC	C12orf45 →	-0.460	-0.367	<.001	.001	3	3
HNSC	S100A9 →	+2.668	+0.456	<.001	<.001	3	3
HNSC	METRNL →	+0.979	+0.325	<.001	.002	3	3
PDAC	ARSI →	+0.845	+0.670	.008	.005	3	3
GBM	PDE4B →	+0.910	+0.478	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,541 associations by consensus.

PCDHGC3 vs PLAUR — PDAC

Explore this scatter interactively →