PCDHGB8P

Across TCGA pan-cancer cohorts, PCDHGB8P RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of PCDHGB8P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where PCDHGB8P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PCDHGB8P is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.

KIRC, BLCA, and BRCA are the cancer types where PCDHGB8P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PCDHGB8P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.164	<.001	12	view →
BLCA	Male	All	+0.228	.036	4	view →
BRCA	Female	All	+0.114	.037	4	view →
HNSC	All	II,III,IV	+0.058	.014	4	view →
THCA	Male	III,IV	−0.108	.019	3	view →
CHOL	All	All	+0.541	.003	2	view →
PRAD	All	All	+0.076	.003	2	view →
LIHC	All	All	+0.055	.028	2	view →
LUAD	All	All	+0.176	.023	1	view →
COAD	Female	III,IV	−0.096	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

PCDHGB8P–KIRC

Open the KIRC breakdown →