PCDHGB5

Across TCGA patient cohorts, PCDHGB5 protein abundance is significantly associated with the RNA expression of many other genes, with 646 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PCDHGB5-associated genes across cancer lineages are FUT11, SMARCA1, and HCFC1R1. Each is linked with PCDHGB5 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHGB5-to-partner and partner-to-PCDHGB5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHGB5 versus FUT11 in LSCC, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGB5→partner) and Y-score (partner→PCDHGB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FUT11 →	+0.779	+0.873	<.001	.004	3	2
LSCC	SMARCA1 →	+1.202	+0.952	<.001	.001	3	1
LSCC	HCFC1R1 →	+0.567	+1.026	.001	.001	3	1
LSCC	EYA1 →	+1.482	+0.952	.008	.001	3	1
LSCC	BNIP3L →	+0.430	+0.676	.007	.004	3	1
LSCC	PANX1 →	+0.660	+0.760	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 646 associations by consensus.

PCDHGB5 vs FUT11 — LSCC

Explore this scatter interactively →