PCDHGB3

Across TCGA patient cohorts, PCDHGB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,117 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible PCDHGB3-associated GO terms across cancer lineages are Regulation of intracellular steroid hormone receptor signaling pathway, Steroid hormone mediated signaling pathway, and Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Each is linked with PCDHGB3 in more than 31 cancer types. Because this analysis shows association rather than direction, both PCDHGB3-to-partner and partner-to-PCDHGB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular steroid hormone receptor signaling pathway grouped by PCDHGB3-low versus PCDHGB3-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGB3→partner) and Y-score (partner→PCDHGB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.072	+0.957	<.001	<.001	3	32
THYM	Steroid hormone mediated signaling pathway →	+0.064	+1.023	<.001	<.001	3	32
THYM	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.061	+1.066	<.001	<.001	3	31
GBM	Obsolete regulation of histone methylation →	+0.077	+0.836	<.001	<.001	2	32
UCS	Establishment of mitotic sister chromatid cohesion →	+0.114	+0.508	<.001	<.001	3	31
UCS	5S class rRNA transcription by RNA polymerase III →	+0.076	+0.442	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,117 associations by consensus.

Regulation of intracellular steroid hormone receptor signaling pathway by PCDHGB3 expression — THYM

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