PCDHGA9

Across TCGA patient cohorts, PCDHGA9 protein abundance is significantly associated with the RNA expression of many other genes, with 379 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PCDHGA9-associated genes across cancer lineages are SPECC1L, TTLL1, and HMGXB4. Each is linked with PCDHGA9 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHGA9-to-partner and partner-to-PCDHGA9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHGA9 versus SPECC1L in GBM, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGA9→partner) and Y-score (partner→PCDHGA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SPECC1L →	-0.309	-0.576	.007	<.001	3	1
GBM	TTLL1 →	-0.399	-0.460	.005	.003	3	1
GBM	HMGXB4 →	-0.378	-0.440	.003	.009	3	1
GBM	CCM2L →	+0.410	+0.452	.008	<.001	3	1
GBM	ALG13 →	-0.262	-0.370	.002	.005	3	1
GBM	AMMECR1 →	-0.379	-0.497	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 379 associations by consensus.

PCDHGA9 vs SPECC1L — GBM

Explore this scatter interactively →