PCDHGA9

Across TCGA patient cohorts, PCDHGA9 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible PCDHGA9-associated genes across cancer lineages are PCNA, Cyclin-B1, and MYH11. Each is linked with PCDHGA9 in more than 3 cancer types. Because this analysis shows association rather than direction, both PCDHGA9-to-partner and partner-to-PCDHGA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by PCDHGA9-low versus PCDHGA9-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGA9→partner) and Y-score (partner→PCDHGA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PCNA →	+0.250	+3.584	.001	.002	3	3
UCEC	Cyclin-B1 →	+0.575	+3.584	.005	.002	3	3
LUSC	MYH11 →	-1.089	-2.312	.010	.035	3	2
SKCM	PREX1 →	-0.266	-2.000	.042	.029	3	2
STAD	ER-alpha →	-0.176	-2.978	.047	.036	3	2
UCEC	MEK1 →	+0.358	+2.247	.007	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

PCNA by PCDHGA9 expression — SKCM

Explore this box plot interactively →