PCDHGA5

Across TCGA patient cohorts, PCDHGA5 protein abundance is significantly associated with the RNA expression of many other genes, with 278 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PCDHGA5-associated genes across cancer lineages are APH1A, SRM, and SMUG1. Each is linked with PCDHGA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHGA5-to-partner and partner-to-PCDHGA5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHGA5 versus APH1A in BRCA, with a Pearson correlation of -0.93.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGA5→partner) and Y-score (partner→PCDHGA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	APH1A →	-0.963	-1.762	.004	.001	3	2
GBM	SRM →	-0.683	-0.690	.009	.007	3	1
GBM	SMUG1 →	-0.498	-0.897	.001	.002	3	1
GBM	PEF1 →	-0.403	-0.839	.007	.003	3	1
GBM	NOC2L →	-0.538	-0.775	<.001	.004	3	1
GBM	RPS6P14 →	+0.301	+1.804	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 278 associations by consensus.

PCDHGA5 vs APH1A — BRCA

Explore this scatter interactively →