PCDHGA4

Across TCGA patient cohorts, PCDHGA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,140 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PCDHGA4-associated GO terms across cancer lineages are Endosomal transport, Protein-containing complex disassembly, and Piecemeal microautophagy of the nucleus. Each is linked with PCDHGA4 in more than 28 cancer types. Because this analysis shows association rather than direction, both PCDHGA4-to-partner and partner-to-PCDHGA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by PCDHGA4-low versus PCDHGA4-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGA4→partner) and Y-score (partner→PCDHGA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Endosomal transport →	+0.094	+1.022	<.001	<.001	3	29
SCLC	Protein-containing complex disassembly →	+0.053	+0.602	<.001	.002	3	29
SCLC	Piecemeal microautophagy of the nucleus →	+0.116	+0.854	<.001	<.001	3	29
THYM	Obsolete selective autophagy →	+0.062	+1.080	<.001	<.001	3	28
CHOL	Negative regulation of protein sumoylation →	+0.090	+0.912	<.001	.001	2	29
SCLC	Autophagosome organization →	+0.069	+1.130	<.001	<.001	2	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,140 associations by consensus.

Endosomal transport by PCDHGA4 expression — SCLC

Explore this box plot interactively →