PCDHGA2

Across TCGA patient cohorts, PCDHGA2 protein abundance is significantly associated with the RNA expression of many other genes, with 718 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDHGA2-associated genes across cancer lineages are TOMM22, PNN, and CHRNA4. Each is linked with PCDHGA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHGA2-to-partner and partner-to-PCDHGA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHGA2 versus TOMM22 in UCEC, with a Pearson correlation of -0.95.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGA2→partner) and Y-score (partner→PCDHGA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TOMM22 →	-0.563	-0.346	.004	.007	3	1
UCEC	PNN →	-0.586	-0.346	.002	.007	3	1
UCEC	CHRNA4 →	+0.033	+0.346	.002	.007	3	1
UCEC	HM13 →	-0.500	-0.346	.003	.007	3	1
UCEC	PSMD7 →	-0.693	-0.346	.002	.007	3	1
UCEC	PLPPR2 →	+0.543	+0.346	.003	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 718 associations by consensus.

PCDHGA2 vs TOMM22 — UCEC

Explore this scatter interactively →