PCDHGA12

Across TCGA patient cohorts, PCDHGA12 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,464 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PCDHGA12-associated proteins across cancer lineages are VIM_S22, SEPTIN2, and SFRP2. Each is linked with PCDHGA12 in more than 4 cancer types. Because this analysis shows association rather than direction, both PCDHGA12-to-partner and partner-to-PCDHGA12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHGA12 versus VIM_S22 in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGA12→partner) and Y-score (partner→PCDHGA12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	VIM_S22 →	+0.795	+0.421	<.001	<.001	3	5
PDAC	SEPTIN2 →	+0.243	+0.394	<.001	<.001	3	5
OV	SFRP2 →	+1.500	+0.627	<.001	<.001	3	5
BRCA	LUM →	+0.843	+0.424	<.001	<.001	3	5
OV	MMP2 →	+0.894	+0.566	<.001	<.001	3	5
OV	THBS2 →	+1.304	+0.413	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,464 associations by consensus.

PCDHGA12 vs VIM_S22 — OV

Explore this scatter interactively →