PCDHGA11

Across TCGA patient cohorts, PCDHGA11 protein abundance is significantly associated with the RNA expression of many other genes, with 2,894 significant associations in total. OV shows the largest number of these associations.

The most reproducible PCDHGA11-associated genes across cancer lineages are CINP, ZNF85, and NHP2P1. Each is linked with PCDHGA11 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHGA11-to-partner and partner-to-PCDHGA11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHGA11 versus CINP in OV, with a Pearson correlation of -0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGA11→partner) and Y-score (partner→PCDHGA11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CINP →	-1.087	-0.884	<.001	<.001	3	2
OV	ZNF85 →	-1.164	-0.952	.001	.002	3	2
OV	NHP2P1 →	-1.735	-0.594	.002	.002	3	2
OV	RCN2 →	-0.998	-0.583	.005	.002	3	2
OV	MPHOSPH10 →	-0.478	-0.639	.004	<.001	3	2
CCRCC	F13A1 →	+2.098	+0.786	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,894 associations by consensus.

PCDHGA11 vs CINP — OV

Explore this scatter interactively →