Across TCGA cell cohorts, PCDHGA1 mutation is significantly associated with the RNA expression of many other genes, with 78 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PCDHGA1-associated genes across cancer lineages are GALP, CHIA, and ADIG. Each is linked with PCDHGA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHGA1-to-partner and partner-to-PCDHGA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHGA1→partner) and Y-score (partner→PCDHGA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	GALP →	+0.040	+4.643	<.001	.008	3	2
URINARY_TRACT	CHIA →	+1.476	+5.087	<.001	.004	3	1
LUNG_NSCLC_LUSC	ADIG →	+0.040	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	MINDY4B →	+0.060	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	OR14A2 →	+0.036	+4.643	<.001	.008	3	1
LUNG_SCLC	OR11G2 →	+0.018	+4.058	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 78 associations by consensus.

Exploration

PCDHGA1 survival (RNA) · tumor vs normal (RNA) · all PCDHGA1 data types