PCDHB9

Across TCGA patient cohorts, PCDHB9 mutation is significantly associated with the RNA expression of many other genes, with 2,932 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDHB9-associated genes across cancer lineages are FOXM1, PSMC3IP, and WDR62. Each is linked with PCDHB9 in more than 3 cancer types. Because this analysis shows association rather than direction, both PCDHB9-to-partner and partner-to-PCDHB9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXM1 grouped by PCDHB9-low versus PCDHB9-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHB9→partner) and Y-score (partner→PCDHB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FOXM1 →	+0.806	+1.999	.004	.009	3	4
COAD	PSMC3IP →	+0.615	+3.200	<.001	.009	3	4
LUSC	WDR62 →	+0.708	+3.807	.002	<.001	3	4
LUAD	MYO19 →	+0.516	+2.247	<.001	.002	3	4
COAD	KIF23 →	+0.657	+3.335	<.001	.005	3	4
UCEC	CHAF1A →	+0.417	+2.291	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,932 associations by consensus.

FOXM1 by PCDHB9 expression — LUAD

Explore this box plot interactively →