PCDHB8

Across TCGA patient cohorts, PCDHB8 protein abundance is significantly associated with the RNA expression of many other genes, with 4,769 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PCDHB8-associated genes across cancer lineages are PIGU, SDHB, and VAMP8. Each is linked with PCDHB8 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHB8-to-partner and partner-to-PCDHB8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHB8 versus PIGU in OV, with a Pearson correlation of -0.88.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHB8→partner) and Y-score (partner→PCDHB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PIGU →	-0.935	-1.705	.002	<.001	3	1
OV	SDHB →	-1.009	-1.906	.009	.004	3	1
OV	VAMP8 →	-0.643	-1.705	.004	<.001	3	1
OV	SLC39A4 →	-2.105	-1.705	.006	<.001	3	1
OV	LSP1P3 →	+0.705	+1.873	.008	.005	3	1
OV	ATP5MG →	-1.160	-1.745	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,769 associations by consensus.

PCDHB8 vs PIGU — OV

Explore this scatter interactively →