PCDHB7

Across TCGA patient cohorts, PCDHB7 protein abundance is significantly associated with the RNA expression of many other genes, with 8,292 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PCDHB7-associated genes across cancer lineages are IL2RB, CCNB1IP1, and SRP54. Each is linked with PCDHB7 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHB7-to-partner and partner-to-PCDHB7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDHB7 versus IL2RB in GBM, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHB7→partner) and Y-score (partner→PCDHB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IL2RB →	-0.783	-0.537	.002	.001	3	1
GBM	CCNB1IP1 →	+0.413	+0.581	.008	.001	3	1
GBM	SRP54 →	+0.435	+0.751	<.001	<.001	3	1
GBM	PRORP →	+0.441	+0.513	.003	.001	3	1
GBM	PSMA6 →	+0.395	+0.542	<.001	.001	3	1
GBM	CSNK2A1 →	+0.241	+0.520	.008	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,292 associations by consensus.

PCDHB7 vs IL2RB — GBM

Explore this scatter interactively →