PCDHB4

Across TCGA cell cohorts, PCDHB4 mutation is significantly associated with the RNA expression of many other genes, with 183 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCDHB4-associated genes across cancer lineages are ANKRD66, OR8B12, and LYZL6. Each is linked with PCDHB4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHB4-to-partner and partner-to-PCDHB4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD66 grouped by PCDHB4-low versus PCDHB4-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHB4→partner) and Y-score (partner→PCDHB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	ANKRD66 →	+0.013	+4.237	.001	.006	3	2
SOFT_TISSUE	OR8B12 →	+0.041	+5.369	<.001	.004	3	2
SOFT_TISSUE	LYZL6 →	+0.019	+5.369	<.001	.004	3	2
SOFT_TISSUE	OR8B3 →	+0.018	+4.930	.002	.008	3	2
BLOOD_Leukemia	SELE →	+0.008	+3.705	<.001	.007	3	2
LARGE_INTESTINE	HSFY1 →	+0.009	+3.192	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 183 associations by consensus.

ANKRD66 by PCDHB4 expression — PANCREAS

Explore this box plot interactively →