PCDHB17P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PCDHB17P mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDHB17P-associated genes across cancer lineages are TSPY8 and MIR3142. Each is linked with PCDHB17P in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHB17P-to-partner and partner-to-PCDHB17P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPY8 grouped by PCDHB17P-low versus PCDHB17P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHB17P→partner) and Y-score (partner→PCDHB17P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTSPY8 →+0.024+8.066<.001.00731
UCECMIR3142 →+0.672+8.066<.001.00731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

TSPY8 by PCDHB17P expression — UCEC

Box plot of TSPY8 in PCDHB17P-low vs PCDHB17P-high samples in UCEC.

Explore this box plot interactively →

Exploration