PCDHB17P

Across TCGA cell cohorts, PCDHB17P mutation is significantly associated with the RNA expression of many other genes, with 273 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCDHB17P-associated genes across cancer lineages are PDCL2, ODF1, and TEX43. Each is linked with PCDHB17P in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHB17P-to-partner and partner-to-PCDHB17P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCL2 grouped by PCDHB17P-low versus PCDHB17P-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHB17P→partner) and Y-score (partner→PCDHB17P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PDCL2 →	+0.141	+2.849	.002	.001	3	2
SKIN	ODF1 →	+0.020	+5.022	<.001	.002	3	1
BLOOD_Leukemia	TEX43 →	+0.141	+5.969	<.001	.001	3	1
LARGE_INTESTINE	GCAT →	+1.344	+3.628	<.001	<.001	3	1
LARGE_INTESTINE	EIF3L →	+0.589	+3.389	<.001	.001	3	1
LARGE_INTESTINE	SAMM50 →	+0.545	+2.502	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 273 associations by consensus.

PDCL2 by PCDHB17P expression — LARGE_INTESTINE

Explore this box plot interactively →