Across TCGA patient cohorts, PCDHB13 mutation is significantly associated with the total protein of many other genes, with 74 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDHB13-associated genes across cancer lineages are Bak, 4E-BP1, and PKC-b-II_pS660. Each is linked with PCDHB13 in more than 4 cancer types. Because this analysis shows association rather than direction, both PCDHB13-to-partner and partner-to-PCDHB13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHB13→partner) and Y-score (partner→PCDHB13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Bak →	+0.170	+1.459	.007	.009	3	5
LUAD	4E-BP1 →	+0.372	+2.334	.004	.018	3	4
COAD	PKC-b-II_pS660 →	-0.321	-2.321	.021	.033	3	4
UCEC	mTOR_pS2448 →	-0.141	-2.249	<.001	<.001	3	4
UCEC	ATM →	-0.461	-1.547	<.001	<.001	3	4
UCEC	TFRC →	+0.563	+1.547	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 74 associations by consensus.

Exploration

PCDHB13 survival (RNA) · tumor vs normal (RNA) · all PCDHB13 data types