PCDHB13

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PCDHB13 mutation is significantly associated with the RNA expression of many other genes, with 186 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCDHB13-associated genes across cancer lineages are IFNA5, OLFM3, and STAU1. Each is linked with PCDHB13 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHB13-to-partner and partner-to-PCDHB13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHB13→partner) and Y-score (partner→PCDHB13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADIFNA5 →+0.030+3.415<.001.00232
BLOOD_LeukemiaOLFM3 →+0.405+2.889.007.00331
BLOOD_LeukemiaSTAU1 →+0.472+3.318.009.00531
BLOOD_LeukemiaPAX1 →+0.026+2.890<.001.00331
BLOOD_LeukemiaGDF5 →+0.039+3.259.001.00631
BLOOD_LeukemiaDPP6 →+0.273+3.108<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 186 associations by consensus.

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