PCDHB10

Across TCGA patient cohorts, PCDHB10 mutation is significantly associated with the RNA expression of many other genes, with 5,903 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDHB10-associated genes across cancer lineages are GBGT1, ADAM33, and CX3CR1. Each is linked with PCDHB10 in more than 4 cancer types. Because this analysis shows association rather than direction, both PCDHB10-to-partner and partner-to-PCDHB10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GBGT1 grouped by PCDHB10-low versus PCDHB10-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHB10→partner) and Y-score (partner→PCDHB10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GBGT1 →	-0.667	-2.571	<.001	.001	3	5
STAD	ADAM33 →	-1.126	-3.459	.001	.005	3	5
STAD	CX3CR1 →	-0.742	-3.421	.004	.005	3	5
STAD	OIP5 →	+0.748	+2.618	.001	.005	3	4
UCEC	KCTD9 →	+0.505	+1.667	<.001	<.001	3	4
LUAD	EIF2B2 →	+0.339	+2.366	.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,903 associations by consensus.

GBGT1 by PCDHB10 expression — COAD

Explore this box plot interactively →