PCDHB10

Across TCGA patient cohorts, PCDHB10 mutation is significantly associated with the total protein of many other genes, with 87 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDHB10-associated genes across cancer lineages are ASNS, ATM, and Caveolin-1. Each is linked with PCDHB10 in more than 4 cancer types. Because this analysis shows association rather than direction, both PCDHB10-to-partner and partner-to-PCDHB10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by PCDHB10-low versus PCDHB10-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHB10→partner) and Y-score (partner→PCDHB10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	ASNS →	+0.684	+3.000	<.001	.036	3	4
COAD	ATM →	-0.523	-2.313	<.001	.006	3	4
LUAD	Caveolin-1 →	-0.907	-3.321	.002	.009	2	5
COAD	eIF4E →	+0.246	+2.334	<.001	.018	3	4
COAD	PCNA →	+0.395	+3.713	<.001	<.001	3	4
UCEC	4E-BP1 →	+0.276	+2.662	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 87 associations by consensus.

ASNS by PCDHB10 expression — BLCA

Explore this box plot interactively →