PCDHB10

Across TCGA cell cohorts, PCDHB10 mutation is significantly associated with the RNA expression of many other genes, with 214 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCDHB10-associated genes across cancer lineages are KCNA5, ASIC5, and H3C11. Each is linked with PCDHB10 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHB10-to-partner and partner-to-PCDHB10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNA5 grouped by PCDHB10-low versus PCDHB10-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHB10→partner) and Y-score (partner→PCDHB10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	KCNA5 →	+0.015	+3.285	.002	.009	3	2
LUNG_SCLC	ASIC5 →	+0.067	+4.269	.001	.005	3	2
LARGE_INTESTINE	H3C11 →	+0.346	+2.831	<.001	<.001	3	2
BLOOD_Leukemia	GUCA2A →	+0.026	+3.969	<.001	.009	3	2
LUNG_NSCLC_LUAD	FBXO40 →	+0.007	+3.604	<.001	.004	3	2
LUNG_NSCLC_LUAD	ADH1A →	+0.045	+3.747	.002	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 214 associations by consensus.

KCNA5 by PCDHB10 expression — BLOOD_Myeloma

Explore this box plot interactively →