PCDHB1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PCDHB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,066 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PCDHB1-associated GO terms across cancer lineages are Protein-containing complex localization, Autophagy of mitochondrion, and Transport along microtubule. Each is linked with PCDHB1 in more than 22 cancer types. Because this analysis shows association rather than direction, both PCDHB1-to-partner and partner-to-PCDHB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-containing complex localization grouped by PCDHB1-low versus PCDHB1-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHB1→partner) and Y-score (partner→PCDHB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SCLCProtein-containing complex localization →+0.057+0.723<.001.001323
SCLCAutophagy of mitochondrion →+0.085+0.678<.001<.001323
SCLCTransport along microtubule →+0.073+0.682<.001<.001322
ESCACytoskeleton-dependent intracellular transport →+0.069+0.315<.001<.001322
STADRegulation of microtubule polymerization or depolymerization →+0.065+0.190<.001<.001322
ESCATelomere organization →+0.077+0.285<.001<.001322
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,066 associations by consensus.

Protein-containing complex localization by PCDHB1 expression — SCLC

Box plot of Protein-containing complex localization in PCDHB1-low vs PCDHB1-high samples in SCLC.

Explore this box plot interactively →

Exploration