PCDHAC1

Across TCGA patient cohorts, PCDHAC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,150 significant associations in total. THCA shows the largest number of these associations.

The most reproducible PCDHAC1-associated GO terms across cancer lineages are Cytosolic transport, Regulation of autophagosome assembly, and Endosomal transport. Each is linked with PCDHAC1 in more than 28 cancer types. Because this analysis shows association rather than direction, both PCDHAC1-to-partner and partner-to-PCDHAC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by PCDHAC1-low versus PCDHAC1-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHAC1→partner) and Y-score (partner→PCDHAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Cytosolic transport →	+0.081	+0.799	<.001	<.001	3	29
SCLC	Regulation of autophagosome assembly →	+0.062	+0.840	.005	<.001	2	29
SCLC	Endosomal transport →	+0.087	+0.857	<.001	<.001	3	28
SCLC	Vesicle cargo loading →	+0.100	+0.653	.001	.002	2	28
STAD	Positive regulation of autophagosome assembly →	+0.083	+0.274	<.001	<.001	3	27
SCLC	Organelle disassembly →	+0.062	+0.714	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,150 associations by consensus.

Cytosolic transport by PCDHAC1 expression — SCLC

Explore this box plot interactively →