Across TCGA patient cohorts, PCDHA9 mutation is significantly associated with the total protein of many other genes, with 84 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDHA9-associated genes across cancer lineages are ER-alpha, Rictor_pT1135, and Ku80. Each is linked with PCDHA9 in more than 5 cancer types. Because this analysis shows association rather than direction, both PCDHA9-to-partner and partner-to-PCDHA9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHA9→partner) and Y-score (partner→PCDHA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ER-alpha →	-0.289	-3.321	.026	.010	3	5
STAD	Rictor_pT1135 →	-0.146	-3.305	.013	.009	3	4
LUSC	Ku80 →	+0.304	+3.000	.028	.033	3	4
LUSC	MYH11 →	-1.018	-3.000	.007	.033	3	4
LUSC	PCNA →	+0.230	+2.709	.007	.003	3	4
COAD	Caspase-7-cleavedD198 →	+0.660	+1.440	.001	.020	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 84 associations by consensus.

Exploration

PCDHA9 survival (RNA) · tumor vs normal (RNA) · all PCDHA9 data types