Across TCGA cell cohorts, PCDHA9 mutation is significantly associated with the mutation status of many other genes, with 2,798 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PCDHA9-associated genes across cancer lineages are ITIH5, ASTN1, and SCRIB. Each is linked with PCDHA9 in more than 4 cancer types. Because this analysis shows association rather than direction, both PCDHA9-to-partner and partner-to-PCDHA9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHA9→partner) and Y-score (partner→PCDHA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ITIH5 →	+3.238	+4.960	<.001	<.001	1	5
STOMACH	ASTN1 →	+3.357	+4.285	.005	.005	1	4
BLOOD_Leukemia	SCRIB →	+2.560	+4.364	.002	.002	1	4
SKIN	SV2B →	+2.925	+2.807	<.001	<.001	1	4
SKIN	SEMA4A →	+4.247	+2.807	.007	.007	1	4
BLOOD_Lymphoma	ATRN →	+3.025	+3.754	.006	.006	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,798 associations by consensus.

Exploration

PCDHA9 survival (RNA) · tumor vs normal (RNA) · all PCDHA9 data types