Across TCGA cell cohorts, PCDHA8 mutation is significantly associated with the RNA expression of many other genes, with 1,191 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCDHA8-associated genes across cancer lineages are CST9, PRMT9, and GLMN. Each is linked with PCDHA8 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHA8-to-partner and partner-to-PCDHA8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHA8→partner) and Y-score (partner→PCDHA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	CST9 →	+0.006	+5.807	<.001	.001	3	2
LARGE_INTESTINE	PRMT9 →	+0.668	+3.502	<.001	.001	3	2
LARGE_INTESTINE	GLMN →	+0.642	+3.502	<.001	.001	3	2
OESOPHAGUS	MRGPRX1 →	+0.146	+4.392	<.001	.003	3	1
OESOPHAGUS	KRTAP19-5 →	+0.192	+4.392	<.001	.003	3	1
BLOOD_Leukemia	MMP27 →	+0.013	+3.969	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,191 associations by consensus.

Exploration

PCDHA8 survival (RNA) · tumor vs normal (RNA) · all PCDHA8 data types