Across TCGA patient cohorts, PCDHA7 mutation is significantly associated with the RNA expression of many other genes, with 6,624 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDHA7-associated genes across cancer lineages are MTIF2, ERLIN1, and TMEM209. Each is linked with PCDHA7 in more than 4 cancer types. Because this analysis shows association rather than direction, both PCDHA7-to-partner and partner-to-PCDHA7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHA7→partner) and Y-score (partner→PCDHA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTIF2 →	+0.326	+1.771	<.001	<.001	3	5
STAD	ERLIN1 →	+0.483	+3.459	.003	.005	3	5
UCEC	TMEM209 →	+0.342	+1.790	.004	.003	3	5
HNSC	TYW1 →	+0.433	+2.608	.005	.006	3	4
UCEC	CDC45 →	+0.544	+2.137	<.001	<.001	3	4
UCEC	DLAT →	+0.573	+2.321	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,624 associations by consensus.

Exploration

PCDHA7 survival (RNA) · tumor vs normal (RNA) · all PCDHA7 data types