Across TCGA patient cohorts, PCDHA7 mutation is significantly associated with the total protein of many other genes, with 55 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDHA7-associated genes across cancer lineages are INPP4B, ASNS, and Caspase-7-cleavedD198. Each is linked with PCDHA7 in more than 3 cancer types. Because this analysis shows association rather than direction, both PCDHA7-to-partner and partner-to-PCDHA7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHA7→partner) and Y-score (partner→PCDHA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	INPP4B →	-0.358	-1.700	.004	.040	3	4
COAD	ASNS →	+0.403	+1.774	.002	.008	3	4
COAD	Caspase-7-cleavedD198 →	+0.979	+1.891	<.001	.027	3	3
LUSC	EGFR →	+0.479	+1.874	.002	.049	3	2
LUSC	HSP70 →	-0.642	-3.897	<.001	<.001	3	2
LUSC	Caspase-3 →	+0.181	+2.337	.018	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

Exploration

PCDHA7 survival (RNA) · tumor vs normal (RNA) · all PCDHA7 data types