Across TCGA patient cohorts, PCDHA4 protein abundance is significantly associated with the RNA expression of many other genes, with 121 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDHA4-associated genes across cancer lineages are STARD3NL, CUBN, and KLHL2. Each is linked with PCDHA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHA4-to-partner and partner-to-PCDHA4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHA4→partner) and Y-score (partner→PCDHA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STARD3NL →	+0.638	+1.121	<.001	.001	3	1
UCEC	CUBN →	+1.640	+0.728	.001	.008	3	1
UCEC	KLHL2 →	+0.969	+1.001	<.001	.006	3	1
UCEC	SLC1A2 →	+0.911	+1.043	.009	.004	3	1
UCEC	CD46 →	+0.711	+1.325	.003	.008	3	1
UCEC	SFRP5 →	+1.429	+1.340	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 121 associations by consensus.

Exploration

PCDHA4 survival (RNA) · tumor vs normal (RNA) · all PCDHA4 data types