Across TCGA cell cohorts, PCDHA4 mutation is significantly associated with the protein abundance of many other proteins, with 205 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PCDHA4-associated proteins across cancer lineages are FOXK2, SLBP, and GOLGA2. Each is linked with PCDHA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHA4-to-partner and partner-to-PCDHA4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHA4→partner) and Y-score (partner→PCDHA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FOXK2 →	+0.474	+2.584	.001	.005	3	2
BLOOD_Leukemia	SLBP →	+0.699	+3.395	.003	.001	3	2
BLOOD_Leukemia	GOLGA2 →	+0.369	+2.621	.006	.003	3	1
BLOOD_Leukemia	MPLKIP →	+0.679	+3.093	.002	.005	3	1
BLOOD_Leukemia	USP39 →	+0.303	+3.376	.006	.002	3	1
BLOOD_Leukemia	MRPL1 →	-0.323	-2.548	.008	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 205 associations by consensus.

Exploration

PCDHA4 survival (RNA) · tumor vs normal (RNA) · all PCDHA4 data types