Across TCGA cell cohorts, PCDHA2 mutation is significantly associated with the RNA expression of many other genes, with 842 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCDHA2-associated genes across cancer lineages are PRR23A, PVALEF, and PPIAL4F. Each is linked with PCDHA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDHA2-to-partner and partner-to-PCDHA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHA2→partner) and Y-score (partner→PCDHA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	PRR23A →	+0.026	+3.584	<.001	.005	3	2
URINARY_TRACT	PVALEF →	+0.044	+3.584	<.001	.009	3	2
LUNG_SCLC	PPIAL4F →	+0.086	+3.256	<.001	.005	3	2
OVARY	ASB18 →	+0.072	+3.844	.005	.001	3	2
LUNG_NSCLC_LUAD	HPCAL4 →	+0.417	+3.292	<.001	.006	3	2
LUNG_NSCLC_LUAD	DSTYK →	+0.485	+3.206	.004	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 842 associations by consensus.

Exploration

PCDHA2 survival (RNA) · tumor vs normal (RNA) · all PCDHA2 data types