Across TCGA cell cohorts, PCDHA2 mutation is significantly associated with the mutation status of many other genes, with 6,591 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCDHA2-associated genes across cancer lineages are KMT2B, USP34, and TICRR. Each is linked with PCDHA2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PCDHA2-to-partner and partner-to-PCDHA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHA2→partner) and Y-score (partner→PCDHA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	KMT2B →	+2.688	+3.196	<.001	<.001	1	6
SKIN	USP34 →	+3.078	+2.532	.005	.005	1	6
BLOOD_Leukemia	TICRR →	+3.932	+3.761	<.001	<.001	1	6
STOMACH	ADAMTS15 →	+4.807	+4.807	.008	.008	1	6
BLOOD_Leukemia	TRPA1 →	+3.347	+3.235	<.001	<.001	1	6
SKIN	SPAG17 →	+2.177	+2.177	.009	.009	1	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,591 associations by consensus.

Exploration

PCDHA2 survival (RNA) · tumor vs normal (RNA) · all PCDHA2 data types