PCDHA11

Across TCGA cell cohorts, PCDHA11 mutation is significantly associated with the RNA expression of many other genes, with 922 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCDHA11-associated genes across cancer lineages are CD164L2, UFSP2, and ASPHD2. Each is linked with PCDHA11 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCDHA11-to-partner and partner-to-PCDHA11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD164L2 grouped by PCDHA11-low versus PCDHA11-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHA11→partner) and Y-score (partner→PCDHA11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	CD164L2 →	+0.056	+4.285	<.001	.003	3	2
BLOOD_Leukemia	UFSP2 →	+0.691	+3.199	<.001	.007	3	2
BLOOD_Leukemia	ASPHD2 →	+0.701	+3.199	.009	.007	3	2
BLOOD_Leukemia	TTC5 →	+0.641	+3.199	.001	.007	3	2
BLOOD_Leukemia	FAM160A1 →	+0.272	+2.800	<.001	.003	3	2
LARGE_INTESTINE	KSR2 →	+0.411	+2.523	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 922 associations by consensus.

CD164L2 by PCDHA11 expression — BLOOD_Myeloma

Explore this box plot interactively →