Across TCGA patient cohorts, PCDHA1 mutation is significantly associated with the RNA expression of many other genes, with 5,450 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDHA1-associated genes across cancer lineages are TXNL4A, RN7SL134P, and NFATC2. Each is linked with PCDHA1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PCDHA1-to-partner and partner-to-PCDHA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHA1→partner) and Y-score (partner→PCDHA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	TXNL4A →	+0.417	+3.087	<.001	<.001	3	5
READ	RN7SL134P →	+0.215	+4.179	<.001	.003	3	4
SKCM	NFATC2 →	-0.766	-1.217	.001	.005	3	4
SKCM	NME1-NME2 →	+0.404	+1.702	.002	.002	3	4
SKCM	CLIC2 →	-0.676	-1.537	.003	<.001	3	4
STAD	IGSF22 →	-0.247	-3.551	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,450 associations by consensus.

Exploration

PCDHA1 survival (RNA) · tumor vs normal (RNA) · all PCDHA1 data types