Across TCGA cell cohorts, PCDHA1 mutation is significantly associated with the mutation status of many other genes, with 6,843 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCDHA1-associated genes across cancer lineages are CDH9, PLXNA4, and KMT2B. Each is linked with PCDHA1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PCDHA1-to-partner and partner-to-PCDHA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHA1→partner) and Y-score (partner→PCDHA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CDH9 →	+5.502	+5.502	.003	.003	1	7
OVARY	PLXNA4 →	+3.310	+4.688	<.001	<.001	1	6
LARGE_INTESTINE	KMT2B →	+1.787	+2.506	<.001	<.001	1	6
SOFT_TISSUE	BCL11B →	+5.502	+5.502	.003	.003	1	6
OVARY	DOCK3 →	+3.047	+4.510	.001	.001	1	6
OVARY	MYO5B →	+4.217	+4.217	.001	.001	1	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,843 associations by consensus.

Exploration

PCDHA1 survival (RNA) · tumor vs normal (RNA) · all PCDHA1 data types