Across TCGA patient cohorts, PCDH9 mutation is significantly associated with the RNA expression of many other genes, with 5,181 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCDH9-associated genes across cancer lineages are NOA1, SV2A, and TPI1. Each is linked with PCDH9 in more than 4 cancer types. Because this analysis shows association rather than direction, both PCDH9-to-partner and partner-to-PCDH9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH9→partner) and Y-score (partner→PCDH9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	NOA1 →	+0.424	+2.273	<.001	.004	3	5
STAD	SV2A →	-0.571	-2.231	.006	.001	3	4
UCEC	TPI1 →	+0.411	+1.865	<.001	<.001	3	4
UCEC	BNIP1 →	+0.255	+1.275	<.001	<.001	3	4
COAD	PIMREG →	+0.579	+4.183	<.001	<.001	3	4
STAD	TXNL4A →	+0.299	+2.475	.009	.009	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,181 associations by consensus.

Exploration

PCDH9 survival (RNA) · tumor vs normal (RNA) · all PCDH9 data types