Across TCGA cell cohorts, PCDH9 mutation is significantly associated with the RNA expression of many other genes, with 99 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCDH9-associated genes across cancer lineages are CCR5, TRAT1, and TNP1. Each is linked with PCDH9 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCDH9-to-partner and partner-to-PCDH9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH9→partner) and Y-score (partner→PCDH9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	CCR5 →	+0.208	+3.974	<.001	.002	3	2
BLOOD_Leukemia	TRAT1 →	+2.115	+3.491	.003	.009	3	2
SOFT_TISSUE	TNP1 →	+1.481	+5.369	<.001	.004	3	1
UPPER_AERODIGESTIVE_TRACT	OR5G3 →	+0.039	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	FAM236A →	+0.120	+5.357	<.001	.003	3	1
SKIN	SCN1A →	+0.103	+2.716	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 99 associations by consensus.

Exploration

PCDH9 survival (RNA) · tumor vs normal (RNA) · all PCDH9 data types