PCDH9-AS4

Across TCGA pan-cancer cohorts, PCDH9-AS4 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated PCDH9-AS4 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PCDH9-AS4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PCDH9-AS4 expression acts as an unfavorable survival marker, although some lineages such as BRCA show a favorable association.

COAD, SKCM, and ESCA are the cancer types where PCDH9-AS4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	II,III,IV	0.039	0.853	<.001	108	view →
SKCM	OS	Tertile	II,III,IV	0.359	0.739	.001	87	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	36	view →
LIHC	OS	Tertile	II,III,IV	0.092	0.696	<.001	36	view →
THCA	OS	Tertile	IV	0.579	1.000	<.001	33	view →
LGG	DFS	Quartile	All	0.260	0.425	<.001	28	view →
READ	OS	Tertile	All	0.183	0.828	<.001	27	view →
BLCA	OS	Tertile	All	0.111	0.447	.029	18	view →
UCEC	DFS	Tertile	All	0.759	0.900	.008	18	view →
STAD	OS	Tertile	IV	0.111	0.433	.002	9	view →
BRCA	OS	Tertile	III,IV	1.000	0.517	.047	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

PCDH9-AS4–COAD (OS)

Open the COAD breakdown →