PCDH7

Across TCGA cell cohorts, PCDH7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,377 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PCDH7-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Cardiac septum development, and Cytoplasmic translation. Each is linked with PCDH7 in more than 6 cancer types. Because this analysis shows association rather than direction, both PCDH7-to-partner and partner-to-PCDH7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by PCDH7-low versus PCDH7-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH7→partner) and Y-score (partner→PCDH7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Negative regulation of gene expression, epigenetic →	+0.057	+2.645	.005	.004	3	7
OESOPHAGUS	Cardiac septum development →	+0.056	+1.710	<.001	<.001	3	7
SOFT_TISSUE	Cytoplasmic translation →	+0.067	+2.225	<.001	.003	3	7
UPPER_AERODIGESTIVE_TRACT	Epigenetic regulation of gene expression →	+0.043	+1.676	.007	.006	3	7
LUNG_SCLC	Cartilage development →	+0.066	+1.715	<.001	<.001	3	7
BREAST	Cardiac septum morphogenesis →	+0.070	+1.606	.005	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,377 associations by consensus.

Negative regulation of gene expression, epigenetic by PCDH7 expression — LIVER

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