PCDH7

Across TCGA cell cohorts, PCDH7 mutation is significantly associated with the RNA expression of many other genes, with 1,057 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCDH7-associated genes across cancer lineages are ANAPC16, FBXW10, and TTC33. Each is linked with PCDH7 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCDH7-to-partner and partner-to-PCDH7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANAPC16 grouped by PCDH7-low versus PCDH7-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH7→partner) and Y-score (partner→PCDH7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	ANAPC16 →	+0.706	+3.070	.004	.008	3	3
BLOOD_Lymphoma	FBXW10 →	+0.132	+4.321	<.001	<.001	3	3
LARGE_INTESTINE	TTC33 →	+0.532	+2.949	.004	<.001	3	3
LARGE_INTESTINE	METTL15 →	+0.374	+2.409	.003	.003	3	3
STOMACH	TCTN3 →	+0.648	+3.070	<.001	.008	3	2
BLOOD_Lymphoma	CCIN →	+0.072	+3.087	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,057 associations by consensus.

ANAPC16 by PCDH7 expression — STOMACH

Explore this box plot interactively →