PCDH20

Across TCGA cell cohorts, PCDH20 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,792 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PCDH20-associated GO terms across cancer lineages are Response to hydrogen sulfide, NK T cell activation, and Aerobic respiration. Each is linked with PCDH20 in more than 5 cancer types. Because this analysis shows association rather than direction, both PCDH20-to-partner and partner-to-PCDH20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to hydrogen sulfide grouped by PCDH20-low versus PCDH20-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH20→partner) and Y-score (partner→PCDH20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Response to hydrogen sulfide →	-0.867	-0.887	.002	.006	3	6
BONE	NK T cell activation →	-0.146	-0.948	.008	.003	3	6
SOFT_TISSUE	Aerobic respiration →	+0.060	+0.655	<.001	.009	3	6
PANCREAS	Negative regulation of osteoblast differentiation →	-0.045	-0.857	.001	.004	3	5
BONE	Cholesterol biosynthetic process →	+0.155	+1.048	.004	.009	3	5
BONE	Regulation of DNA repair →	+0.072	+1.096	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,792 associations by consensus.

Response to hydrogen sulfide by PCDH20 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →