PCDH12

Across TCGA patient cohorts, PCDH12 protein abundance is significantly associated with the RNA expression of many other genes, with 3,266 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PCDH12-associated genes across cancer lineages are F2RL3, DYSF, and ESAM. Each is linked with PCDH12 in more than 3 cancer types. Because this analysis shows association rather than direction, both PCDH12-to-partner and partner-to-PCDH12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDH12 versus F2RL3 in CCRCC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH12→partner) and Y-score (partner→PCDH12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	F2RL3 →	+1.168	+0.487	.003	.002	3	3
LSCC	DYSF →	+0.729	+0.381	<.001	<.001	3	3
CCRCC	ESAM →	+0.733	+0.458	.003	.004	2	4
CCRCC	EGFL7 →	+0.801	+0.441	.003	.006	3	3
LSCC	COL4A2 →	+0.819	+0.454	<.001	<.001	3	3
GBM	ANKRD1 →	+1.456	+0.572	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,266 associations by consensus.

PCDH12 vs F2RL3 — CCRCC

Explore this scatter interactively →