PCDH12

Across TCGA cell cohorts, PCDH12 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,681 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PCDH12-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of myoblast fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with PCDH12 in more than 12 cancer types. Because this analysis shows association rather than direction, both PCDH12-to-partner and partner-to-PCDH12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by PCDH12-low versus PCDH12-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH12→partner) and Y-score (partner→PCDH12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of myoblast fusion →	+0.174	+0.285	<.001	.002	3	13
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.183	+0.285	<.001	.002	3	12
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.162	+0.295	<.001	.002	3	12
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.176	+0.285	<.001	.002	3	11
OESOPHAGUS	Cytoplasmic translation →	+0.128	+0.268	.001	.004	3	11
LUNG_SCLC	Protein sumoylation →	+0.072	+0.350	.004	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,681 associations by consensus.

Regulation of myoblast fusion by PCDH12 expression — OESOPHAGUS

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