PCDH11Y

Across TCGA patient cohorts, PCDH11Y protein abundance is significantly associated with the RNA expression of many other genes, with 10,195 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PCDH11Y-associated genes across cancer lineages are SPARC, SFRP2, and LMOD1. Each is linked with PCDH11Y in more than 5 cancer types. Because this analysis shows association rather than direction, both PCDH11Y-to-partner and partner-to-PCDH11Y results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PCDH11Y versus SPARC in OV, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH11Y→partner) and Y-score (partner→PCDH11Y) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SPARC →	-1.085	-0.582	<.001	<.001	3	6
OV	SFRP2 →	-2.975	-0.714	<.001	<.001	3	6
OV	LMOD1 →	-1.035	-0.830	<.001	<.001	3	6
OV	MSRB3 →	-0.876	-0.598	<.001	<.001	3	6
LSCC	SRPX →	-0.987	-0.337	<.001	<.001	3	5
OV	MEDAG →	-1.204	-0.562	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,195 associations by consensus.

PCDH11Y vs SPARC — OV

Explore this scatter interactively →