PCDH10

Across TCGA cell cohorts, PCDH10 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,321 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PCDH10-associated GO terms across cancer lineages are Neuroblast differentiation, Regulation of microtubule polymerization or depolymerization, and Negative regulation of osteoclast development. Each is linked with PCDH10 in more than 6 cancer types. Because this analysis shows association rather than direction, both PCDH10-to-partner and partner-to-PCDH10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neuroblast differentiation grouped by PCDH10-low versus PCDH10-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH10→partner) and Y-score (partner→PCDH10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Neuroblast differentiation →	+1.128	+1.598	<.001	.001	3	6
OVARY	Regulation of microtubule polymerization or depolymerization →	+0.064	+0.727	<.001	<.001	3	6
SKIN	Negative regulation of osteoclast development →	+0.633	+1.091	.003	.004	3	6
OVARY	Epigenetic regulation of gene expression →	+0.050	+0.771	.001	.006	3	6
BREAST	Regulation of microtubule cytoskeleton organization →	+0.046	+1.057	<.001	.002	3	6
OVARY	Sodium ion homeostasis →	-0.218	-1.076	.002	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,321 associations by consensus.

Neuroblast differentiation by PCDH10 expression — CNS

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