PCDH10

Across TCGA cell cohorts, PCDH10 mutation is significantly associated with the RNA expression of many other genes, with 1,399 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCDH10-associated genes across cancer lineages are HTR1A, INSL5, and NUTM2A. Each is linked with PCDH10 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCDH10-to-partner and partner-to-PCDH10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HTR1A grouped by PCDH10-low versus PCDH10-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDH10→partner) and Y-score (partner→PCDH10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	HTR1A →	+0.030	+5.087	<.001	.004	3	2
SKIN	INSL5 →	+0.025	+2.619	.007	.002	3	2
SKIN	NUTM2A →	+0.381	+3.125	<.001	.008	3	2
LARGE_INTESTINE	METTL4 →	+0.564	+2.289	<.001	<.001	3	2
LARGE_INTESTINE	CEP192 →	+0.631	+1.906	<.001	.001	3	2
LARGE_INTESTINE	NISCH →	+0.647	+2.082	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,399 associations by consensus.

HTR1A by PCDH10 expression — URINARY_TRACT

Explore this box plot interactively →