Across TCGA patient cohorts, PCBP3 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCBP3-associated genes across cancer lineages are mTOR_pS2448, Notch1, and ATM. Each is linked with PCBP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCBP3-to-partner and partner-to-PCBP3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCBP3→partner) and Y-score (partner→PCBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.132	-2.102	.009	.016	3	2
UCEC	Notch1 →	+0.201	+2.137	<.001	.001	3	2
UCEC	ATM →	-0.474	-1.807	.002	.004	3	2
UCEC	Bak →	+0.202	+1.906	.018	.014	3	2
UCEC	c-Met_pY1235 →	+0.054	+1.247	.034	.045	3	2
UCEC	4E-BP1 →	+0.284	+2.837	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Exploration

PCBP3 survival (RNA) · tumor vs normal (RNA) · all PCBP3 data types