PCBP2P3

Across TCGA pan-cancer cohorts, PCBP2P3 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated PCBP2P3 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PCBP2P3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PCBP2P3 expression acts as an unfavorable survival marker, although some lineages such as ESCA and BRCA show a favorable association.

KIRC, UVM, and ESCA are the cancer types where PCBP2P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	IV	0.281	0.555	.010	81	view →
UVM	DFS	Tertile	All	0.273	0.769	.006	60	view →
ESCA	OS	Median	III,IV	0.763	0.410	<.001	50	view →
LUSC	OS	Tertile	III,IV	0.460	0.727	.002	39	view →
CESC	DFS	Tertile	All	0.301	0.585	.004	36	view →
KIRP	OS	Tertile	II,III,IV	0.111	0.769	<.001	27	view →
LIHC	DFS	Tertile	III,IV	0.103	0.436	.004	27	view →
BRCA	OS	Tertile	III,IV	0.982	0.886	.011	24	view →
ACC	OS	Tertile	II,III,IV	0.879	0.437	.012	21	view →
LUAD	DFS	Tertile	All	0.144	0.413	.007	9	view →
OV	OS	Tertile	IV	0.787	0.551	.032	8	view →
THYM	OS	Tertile	All	0.586	0.919	.032	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

PCBP2P3–KIRC (DFS)

Open the KIRC breakdown →